Broad range of diseases treated

The department treats the following types of conditions:

  • Anemia of various causes
    nutritional deficit, blood cell damage and chronic red blood cell diseases, such as spherocytosis, sickle cell anemia, and thalassemia.
  • White blood cell conditions
    including various neutropenic (low white blood cell count) conditions.
  • Platelet disorders
    the department has a wealth of expertise in immune thrombocytopenic purpura (ITP), the most common platelet disorder in children.
  • Bone marrow failure syndromes
  • Diseases of excessive bleeding and thrombophilia 
    both heredity and congenital.
  • Histiocytosis
    the department has extensive experience in treating Langerhans cell histiocytosis.

Malignant diseases in children:

  • Acute and chronic leukemia
  • Brain tumors
    patient care is provided in collaboration with the Department of Pediatric Neurosurgery.
  • Bone and soft tissue tumors
    patient care provided in collaboration with the Tel Aviv Sourasky Medical Center’s National Oncological Orthopedics Department.
  • Lymph node cancer
    lymphoma such as Hodgkin’s lymphoma.
  • Tumors of the kidneys, adrenal glands, testicles and ovaries
  • Rare malignant pediatric tumors

Treatment and tests performed by the department

  • Blood tests
    to minimize wait times for blood counts, testing is performed on-site in the department and the results are received within minutes.
  • Hematological investigations and diagnostics
    including bone marrow testing and spinal taps.
    These tests are performed pain-free with the help of the Tel Aviv Medical Center’s Dream Service (pediatric service that helps children undergo treatment and testing under sedation).
  • Various blood and blood product transfusions
  • Intravenous iron supplementation
  • Immunotherapy treatments
    including immunoglobulins, Rituximab (Mabthera), and anti-D.
  • Chemotherapy administrations
    the range of oral, peripheral intravenous, and central venous catheter administrations, performed according to national and international protocols.

Pediatric bone marrow transplantations

The Pediatric Hemato-oncology Department performs a full array of bone marrow transplants (BMT) for children, sourced by self-donated (autologous) marrow and peripheral blood donations and donations from a related or unrelated donor (allogeneic).
Self-donated transplants are performed for malignant conditions, such as recurrent lymphoma, metastasizing bone cancers, high-risk neuroblastoma, and specific types of brain tumors.
Allogeneic BMTs treat malignant diseases, such as hematologic (blood) cancers and non-malignant diseases, such as congenital immunodeficiency states, metabolic disorders, and hereditary blood diseases.
Pre-transplant care The pediatric BMT service offers pre-transplant care, such as transplant-type decision-making and multidisciplinary testing to prepare the donor and the patient for the procedure.

Transplant accommodations

Transplants are performed in specially designed rooms to accommodate the unique needs of children and to protect the patient from life-threatening infections; rooms feature positive pressure and air filtration systems.Departmental bone marrow transplant services offer essential medical expertise and complementary services to patients with complex health conditions.Post-transplant care Following the transplant, the patient returns home and remains under close, extended follow-up by the Post-BMT Clinic. During this recovery period, the patient is monitored for successful acceptance of the transplant, tracked for immune system recovery, and treated for potential complications.

The Pediatric Bone Marrow Transplantation Unit is recognized by the European Group for Blood and Marrow Transplantation (EBMT) as an international BMT center for bone marrow transplantation from familial as well as non-familial donors and for autologous transplant.